Wednesday, 15 October 2025
Jaisalmer bus fire: Jammed door trapped passengers; bodies being verified
Jaisalmer Bus Accident: भजनलाल सरकार के मंत्री ने माना जैसलमेर बस हादसा किसी न किसी लापरवाही के कारण हुआ
राजस्थान के जैसलमेर के वार म्यूजियम के पास बस में लगी आग की घटना ने हर किसी को हैरान कर दिया है। बताया जा रहा है कि शार्ट सर्किट के कारण बस आगजनी का शिकार हुई। इस दुर्घटना में अब तक 21 लोगों की मौत की हो चुकी है। 4 मरीजों की हालत गंभीर बताई जा रही।
राजस्थान के जैसलमेर में हुए बस अग्निकांड में घायल एक 10 साल के बच्चे ने इलाज के दौरान जोधपुर में दम तोड़ दिया है। इस दुखद हादसे में अब तक 21 लोगों की मौत हो गई है। 4 मरीजों को वेंटिलेटर पर रखा हुआ है, जिनकी हालत गंभीर बताई जा रही है। वहीं इस घटना के बाद सूबे की सीएम भजनलाल शर्मा भी खुद जैसलमेर पहुंचे थे और घटनास्थल का जायजा लिया था। उन्होंने पोकरण विधायक महन्त प्रताप पुरी, जैसलमेर जिला कलेक्टर प्रतापसिंह नाथावत, पुलिस अधीक्षक अभिषेक शिवहरे सहित तमाम जिले के अधिकारियों से घटना का फीडबैक लिया है। फिर अस्पताल पहुंचकर घायलों से भी मिले। इधर पीएम मोदी और राष्ट्रपति द्रौपदी मुर्मू ने हादसे पर दुख जताया है। उधर, बुधवार को जोधपुर जिला प्रभारी मंत्री मदन दिलावर ने महात्मा गांधी अस्पताल पहुंचे। उन्होंने माना कि हादसा किसी न किसी लापरवाही के कारण हुआ है और कहा कि जांच के बाद जो भी तथ्य सामने आएंगे, उसके आधार पर कार्रवाई की जाएगी।
हादसा किसी न किसी लापरवाही के कारण हुआ है- मंत्री मदन दिलावर
जोधपुर जिला प्रभारी मंत्री मदन दिलावर ने महात्मा गांधी अस्पताल पहुंचकर जैसलमेर बस हादसे के घायलों से मुलाकात की है। उन्होंने कहा कि सरकार घायलों के बेहतर इलाज के लिए हरसंभव प्रयास कर रही है और मृतकों के परिजनों के साथ खड़ी है। मंत्री ने माना कि हादसा किसी न किसी लापरवाही के कारण हुआ है और कहा कि जांच के बाद जो भी तथ्य सामने आएंगे, उसके आधार पर कार्रवाई की जाएगी। मुआवजे के सवाल पर उन्होंने कहा कि फिलहाल सरकार की पहली प्राथमिकता घायल लोगों को बचाना है और भविष्य में ऐसी घटनाओं को रोकने के लिए सख्त कदम उठाए जाएंगे।
बस मालिक, ड्राइवर और कंडेक्टर के खिलाफ केस दर्ज
जैसलमेर में निजी बस में आगजनी का मामले में अब बस मालिक, ड्राइवर और कंडेक्टर के खिलाफ मामला दर्ज हुआ है। बस में सेफ्टी उपकरण नहीं होने समेत अन्य आरोप के साथ जैसलमेर सदर थाने में मामला दर्ज कराया गया है। हादसे में जान गंवाने वाले पत्रकार राजेन्द्र सिंह चौहान के भाई चंदनसिंह ने केस दर्ज कराया है। मंगलवार को हुए इस हादसे में 19 यात्रियों की मौके पर ही मौत हो चुकी थी और 2 ने जोधपुर अस्पताल में इलाज के दौरान दम तोड़ा है।
बस अग्निकांड के बाद 7 लोगों के तलाश, हादसे की आशंका
जैसलमेर बस अग्निकांड में अब तक 21 लोगों की मौत हो चुकी है। जोधपुर में 14 घायलों को इलाज जारी है। वहीं करीब 7 लोगों के लापता होने की भी जानकारी सामने आई है। इन सात लोगों के हादसे के वक्त बस में होने की आशंका जताई जा रही है।
source:https://navbharattimes.indiatimes.com/
Saturday, 13 August 2022
India message to China on Taiwan: Avoid actions to change status quo
In its first statement since US House Speaker Nancy Pelosi’s visit to Taipei 10 days ago which angered China and led to PLA military drills, India on Friday called for “exercise of restraint” and to avoid “unilateral actions to change (the) status quo” over Taiwan.
It did not spell out the One-China policy, and instead said that the government’s “relevant” policies are “well-known and consistent” and “do not require reiteration”.
Responding to questions on India’s talks with NATO, Arindam Bachi, spokesperson for the Ministry of External Affairs, said, “India and NATO have kept in touch in Brussels at different levels for quite some time now. This is part of our contacts with various stakeholders on global issues of mutual interest.”
The Indian Express reported Thursday that New Delhi held its first political dialogue with NATO in Brussels on December 12, 2019. The talks were attended by senior officials including from the Ministry of External Affairs and the Ministry of Defence.
To questions on the Taiwan issue, Bagchi said, “Like many other countries, India too is concerned at recent developments. We urge the exercise of restraint, avoidance of unilateral actions to change status quo, de-escalation of tensions and efforts to maintain peace and stability in the region.”
On the question of the One-China policy, the MEA spokesperson said, “India’s relevant policies are well-known and consistent. They do not require reiteration.”
India does not have formal diplomatic ties with Taiwan yet as it adheres to the One-China policy.
Without naming China, New Delhi also called Beijing’s blocking of the proposal to designate Pakistan-based Abdul Rauf Azhar as a global terrorist as “unfortunate”.
Referred to as Abdul Rauf Asghar in UN documents, he is the brother of Jaish-e-Mohammed (JeM) chief Masood Azhar and deputy chief of the proscribed terror group.
“We note with regret that a ‘technical hold’ has been placed on the listing proposal for Abdul Rauf Asghar. It is unfortunate that when it comes to our collective battle against terrorism, the international community has been unable to speak in one common voice,” Bagchi said.
He quoted Ruchira Kamboj, India’s Permanent Representative to the UN in New York, who, during the UNSC Open Debate on August 9, had flagged this concern categorically to all members: “There should be no double standards in dealing with terrorists.”
“The practice of placing holds and blocks without giving any justification must end. It is most regrettable that genuine and evidence based listing proposals pertaining to some of the most notorious terrorists in the world are being placed on hold. Double standards and continuing politicization have rendered the credibility of the Sanctions Regime at an all time low,” Kamboj said.
Bagchi said that Abdul Rauf was actively involved in terrorist attacks such as hijacking of Indian Airlines aircraft IC-814 in 1999, the Parliament terror attacks in 2001 and the terror attacks at the Indian Army camp in Kathua in 2014 and at the IAF base in Pathankot in 2016.
“The practice of placing holds and blocks without giving any justification must end. It is most regrettable that genuine and evidence based listing proposals pertaining to some of the most notorious terrorists in the world are being placed on hold. Double standards and continuing politicization have rendered the credibility of the Sanctions Regime at an all time low,” Kamboj said.
Bagchi said that Abdul Rauf was actively involved in terrorist attacks such as hijacking of Indian Airlines aircraft IC-814 in 1999, the Parliament terror attacks in 2001 and the terror attacks at the Indian Army camp in Kathua in 2014 and at the IAF base in Pathankot in 2016.
Abdul Rauf, he said, has been proscribed under Indian and US laws already, and therefore “the placing of the “technical hold” against such wanted terrorist is most uncalled for.”
“India will continue pursuing its principled position of bringing these terrorists to justice, including through the UNSC 1267 Sanctions Regime,” he said.
On the Chinese Foreign Ministry saying that it was “completely unjustified for certain countries to cite the so-called security concerns” to pressure Sri Lanka — in the context of the Sri Lanka Foreign Ministry asking China to “defer” the arrival of the Yuan Wang 5, a military vessel, at its southern port of Hambantota – the MEA spokesperson said, “We reject the insinuations in the statement about India. Sri Lanka is a sovereign country and makes its own independent decisions.”
He said as far as India-Sri Lanka relations are concerned, “you are aware of the centrality that Sri Lanka occupies in our Neighbourhood First policy. India has extended this year itself an unprecedented support of over US$ 3.8 billion for ameliorating the serious economic situation in Sri Lanka. India also is fully supportive of its democracy, stability and economic recovery.”
On India-China relations, Bagchi said, “We have consistently emphasized the necessity of mutual respect, mutual sensitivity and mutual interests as a basis for the development of ties.”
“With regard to our security concerns, this is the sovereign right of every country. We will make the best judgment in our own interest. This naturally takes into account the prevailing situation in our region, especially in the border areas,” he said.
Salman Rushdie On Ventilator After Stabbing, Attacker Identified: 10 Facts
The author's agent said that Salman Rushdie will likely lose an eye and suffered severed nerves in an arm and damage to his liver.
New Delhi: Author Salman Rushdie was stabbed in the neck and abdomen at a literary event in New York, US, on Friday. The 75-year-old author is on ventilator and could lose an eye. Police have identified his attacker.
1.The author's agent said that Salman Rushdie suffered severed nerves in an arm and damage to his liver, and could lose an eye. "The news is not good," Andrew Wylie, his agent, wrote in an email. "Salman will likely lose one eye; the nerves in his arm were severed; and his liver was stabbed and damaged."
2.New York state police identified his attacker as Hadi Matar, 24, from New Jersey. "The motive behind the attack remain unclear," officials said.
3.A preliminary review of Matar's social media showed him to be sympathetic to "Shia extremism" and the causes of Iran's Islamic Revolutionary Guard (IRGC).
4.Mr Rushdie was repeatedly stabbed by Hadi Matar who rushed to the stage and attacked him. Henry Reese, the interviewer, also suffered a head injury in the attack.
5.Visuals and images circulating on social media showed some people rushing to the stage and taking the suspect to the ground, before a trooper present at the event arrested him.
6.A doctor in the audience administered medical care until emergency first responders arrived. Mr Rushdie was then airlifted to the hospital where he underwent an emergency surgery.
7.The attack occurred as Rushdie was about to give a speech at the Chautauqua Institution near the New York city. There were around 2,500 people in the audience, who were evacuated later. "What many of us witnessed today was a violent expression of hate that shook us to our core," the Chautauqua Institution said in a statement following the attack.
8.US National Security Advisor Jake Sullivan termed the attack as "appalling" and "reprehensible". "All of us in the Biden-Harris Administration are praying for his speedy recovery." Mr Sullivan said in a statement. New York governor Kathy Hochul too condemned the stabbing and hailed Rushdie as "an individual who has spent decades speaking truth to power."
9.A British citizen of Indian origin - living in the US for the past 20 years - Salman Rushdie has faced threats for decades over his 1988 book, The Satanic Verses. The novel was considered by some clerics as disrespectful to the Prophet Mohammed.
10.A reward was put on his head by Iranian leader Ayatollah Ruhollah Khomeini calling for his assassination. He spent nearly a decade under police protection in the United Kingdom, hiding and changing houses repeatedly. Mr Rushdie began to emerge from his life on the run after the Iranian government in 1998 said it won't enforce that 'fatwa' or edict. Since 2000, Rushdie has lived in the United States.
11.
Friday, 24 June 2022
Norway: Two dead, several wounded in shooting at nightclub in Oslo
The Oslo police said the suspect was apprehended after he killed two and injured several people at a nightclub in the Norwegian capital.

Two people have been shot dead in a shooting at a nightclub in Oslo.(Representative image)
Two people were killed and several severely wounded in a shooting at a nightclub in Norway's capital Oslo, Norwegian police said early on Saturday.
A suspect was apprehended nearby, police added.
"Two people are confirmed dead," the Oslo police department said in a tweet.
Source https://www.hindustantimes.com/
Maharashtra Political Crisis News Live Updates: ‘No orders issued by CM or HMO to withdraw security of rebel MLAs,’ says state Home Minister
Maharashtra Political Crisis News Live Updates: Maharashtra Home Minister Dilip Walse Patil denied claims made by rebel Shiv Sena leader Eknath Shinde on Saturday that the protection of Shiv Sena MLAs has been withdrawn by the Maharashtra Chief Minister and HMO. “There have been on orders issues either by the CM or the Home Ministry to withdraw the security of any MLA. Allegations being levelled to this effect are mischievous and false,” Patil said.
The Shiv Sena has sent the names of four more rebel MLAs to the Maharashtra Assembly deputy speaker for initiating action of disqualification against them, a senior leader told PTI. The party will also issue notices to 16 MLAs of the rebel faction and ask them to respond by Monday, Sena MP Arvind Sawant here on Friday. The four legislators whose names were forwarded to the deputy speaker were Sanjay Raymulkar, Chiman Patil, Ramesh Bornare and Balaji Kalyankar, he said.
Taking dissident Shiv Sena MLAs head on, Maharashtra Chief Minister Uddhav Thackeray on Friday accused them of betrayal and challenged them to try and wean away common party workers as he slammed rebel leader Eknath Shinde and also tore into the BJP, saying it wants to “finish off” his outfit and does not want to share its Hindu votebank.
Source:https://indianexpress.com/
Friday, 26 November 2021
Indian Besan Laddu Recipe | Besan Ke Laddu |बेसन के लड्डू हलवाईके जैसे
Ingredients
Besan – 500 gms
Turmeric – 5 gms
Ghee – 375 gms
Sugar fine grain or Burra – 1.25 kg
Almonds & Pista chopped – handful
Besan Ladoo - No one can resist the smell of Besan when you cook with ghee. No festivity is complete without a methai, and nothing compares if it is home made.
Method
How to make Besan Ladoo
For the mixture:
1- Add 175 gms of ghee in the wok and melt it.
2- Add 250 gms of chickpea flour in melted ghee on the low-medium flame.
3- Roast while continuously stirring it to avoid lumps.
4- Add more 1 tsp of ghee if the mixture appears dry.
5- Sprinkle some water to make the mixture uneven.
6- Again, roast it until water disappears.
7- Switch off the flame but, don’t stop stirring for 1-2 minutes.
8- Pour the mixture in another bowl to slightly cool it quickly.
9- Dry roast ¼ cup of Muskmelon seeds until they expand and their colour changes.
10- Pour them in a separate bowl to avoid them from over roasting.
11- Keep on stirring the mixture in intervals also.
12- Touch and check the temperature of the mixture.
13- Add 250 gms of Tagar, roasted Muskmelon seeds, 1 tsp of coarsely grounded green cardamoms and 1 smaller sized grated Nutmeg in the mixture.
14- Mix all the ingredients properly
Suggestions:
1- You can increase or decrease the quantity of sugar according to your taste.
2- The thicker sized chickpea flour is required to make these Ladoos.
3- If you are using tagar which is available in the market then, use a ½ proportion of the finer sized boora and a ½ proportion of the larger sized boora.
4- Cook sugar syrup until it appears white.
5- If clods appear then, break them and filter on a strainer.
6- The ratio of Ghee, Tagar, and Chickpea flour should be equal for the Ladoo.
7- 1 cup of chickpea flour is equal to 125 grams.
8- While roasting continuously stir Chickpea flour to the formation of lumps.
9- Press and stir the mixture in case lumps appear.
10- Ladoo sticks to the throat only when it has not properly roasted.
11- Roast until a soothing aroma arises from the mixture and it appears darks too.
12- Roast Chickpea flour on the low flame for a while to avoid its raw taste.
13- Save some quantity of Ghee for the further process.
14- Chickpea flour expands by adding water.
15- Switch off the flame but, don’t stop stirring to avoid it burning from the bottom.
16- The mixture loses its consistency when Tagar is mixed in the warm mixture.
17- You can add any dry fruit in ladoos but make sure they are roasted to increase its shelf life.
18- You can make ladoo of your desired size.
19- In case Ladoo is still sticky then, store them in the refrigerator for a while.
20- You can add ¼ tsp turmeric powder in 250 grams of Ladoo for better colour or you can add the food colour.
21- The ladoo splits when Tgar has not mixed in the warm mixture.You can avoid this issue by adding some amount of the melted ghee in it.
Please leave your comments and suggestions in the comments section below.
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Saturday, 31 July 2021
Google will stop account sign-in for users running these old Android versions
Google is ending sign-in support for devices running on very old versions of Android. The tech giant is sending emails to users saying sign-in will not be supported on Android version 2.3.7 and lower. In order to continue using Google apps on their phones, they must upgrade to Android version 3.0 or higher.
“Signing in to your account on Google apps will no longer be supported on phones with Android version 2.3.7 or lower starting Sep. 27” reads the email received by some Google users. This means that starting September 27, those running Android version 2.3.7 or lower will not be able to sign into their accounts. These include Android 1.0, 1.1 (unnamed), 1.5 Cupcake, 1.6 Donut, 2.0 Eclair, 2.2 Froyo, and 2.3 Gingerbread.
In the email, Google says that the move is aimed to “help protect your account’s security. Actions like system and an application-level sign will result in a “username or password error”.
According to a Google support page, the following cases will sing-in error:
Perform a factory reset of your device and try to sign in.
Change your password either on the device or on a different device, which then signs you out everywhere else. When you try to sign in again, you will receive an error message.
Remove your account from your device and re-add it.
Create an account on the device.
However, users will still be able to sign in to their account on the phone's browser. “If you cannot update your device to a newer Android version (3.0+), you can try to log into your Google account on your device’s web browser. You can still use some Google services when logged into Google on your device’s web browser” Google says.
Source:https://timesofindia.indiatimes.com
Google swipes left on 'Sugar Dating' apps, will uninstall them from Play Store by Sept 1
Google is enforcing a blanket ban on all such apps such as SDM, Spoiler, and Sugar Daddy. For those uninitiated, Sugar Dating apps allow elderly people to date younger people to overcome loneliness.
Saturday, 20 March 2021
Covid: France and Poland increase lockdown measures as infections surge
France and Poland have reintroduced partial lockdowns as both countries battle a sharp rise in Covid infections in recent weeks.
Some 21 million people in 16 areas of France, including the capital Paris, are affected as the country fears a third wave.
In Poland, non-essential shops, hotels, cultural and sporting facilities are now closed for three weeks.
The country has the highest new daily rates of Covid cases since November.
Coronavirus cases are also rising exponentially in Germany, with Chancellor Angela Merkel warning it is likely that the country will now need to apply an "emergency brake" and re-impose lockdown measures.
Covid wave intensifies in Central Europe
Why is the EU having vaccine problems?
The vaccine rollout across the European Union has been hindered by delayed deliveries, as well as the suspension in several countries of the use of the Oxford-AstraZeneca Covid-19 vaccine, over fears of possible side effects.
What's the situation in France and Poland?
In France, the partial lockdown took effect from midnight on Friday.
Trains leaving Paris for parts of the country where lockdown restrictions do not apply, such as Brittany and Lyon, were reportedly fully booked hours before the measures were due to come into effect.
Traffic jams were reported on several roads leaving the capital.
The new restrictions are not be as strict as the previous lockdown, with people allowed to exercise outdoors.
Non-essential businesses are shut, but schools remain open, along with hairdressers if they follow a "particular sanitary protocol".
France has reported more than 4.2 million infections since the start of the outbreak, with nearly 92,000 Covid-related deaths, according to the data compiled by Johns Hopkins University in the US.
In Poland, the three-week lockdown began on Saturday.
Polish health officials earlier warned the nationwide restrictions were necessary because of a rampant British variant of Covid-19 in the country. The variant now makes up more than 60% of infections.
Poland has had more than two million confirmed infections, and nearly 49,000 deaths, according to Johns Hopkins University.
Germany said on Friday it was now classifying neighbouring Poland as high risk. This means that from Sunday anyone crossing the border from Poland must provide a negative coronavirus test.
What's the latest on the AstraZeneca vaccine?
Despite assurances from the European medicines regulator that the AstraZeneca vaccine is safe and effective, some countries remain reluctant to resume their campaigns using the jab.
Finland's health authority has announced a pause in its use of the vaccine that will last at least a week.
The move, which follows two reports of blood clots in patients who had received the jab in the country, was said to be a precautionary measure.
Is the Oxford-AstraZeneca vaccine safe?
Is Europe's AstraZeneca jab decision-making flawed?
Meanwhile, Sweden, Denmark and Norway said on Friday that they needed more time to determine whether they should resume AstraZeneca inoculations.
Germany, Italy, France, Spain and the Netherlands are among the countries that have restarted their AstraZeneca vaccination campaigns.
Health authorities in France have recommended that the vaccine be offered only to people aged 55 and over.
The European Medicines Agency (EMA) reviewed the jab after 13 European countries suspended use of the vaccine over fears of a link to blood clots.
It found the jab was "not associated" with a higher risk of clots.
The World Health Organization (WHO) has urged countries to continue using the AstraZeneca vaccine.
On Friday, experts at the WHO said the vaccine had "tremendous potential to prevent infections and reduce deaths across the world".
"The available data do not suggest any overall increase in clotting conditions such as deep venous thrombosis or pulmonary embolism following administration of Covid-19 vaccines," the WHO's Global Advisory Committee on Vaccine Safety said in a statement.
Other European leaders have sought to reassure citizens that the Oxford-AstraZeneca jab is safe.
Italy's Prime Minister Mario Draghi, 73, said he would happily have the vaccine, but that he had "not yet made a booking".
His French counterpart, 55-year-old Jean Castex, received an AstraZeneca dose on Friday.
source:https://www.bbc.com
Australia warned of 'life-threatening' flash floods
Emergency authorities in Australia are warning of "life threatening" flash floods as torrential rains batter parts of the country's east coast.
Dozens of people have been rescued from floodwaters, and residents in many low-lying communities of New South Wales have been ordered to leave their homes.
Police say hundreds of people have flocked to evacuation centres in areas north of the city of Sydney.
Major roads have been shut. Footage has emerged of a house being swept away.
Dams around Sydney are expected to overflow over the weekend, WaterNSW warns.
Up to 100mm (four inches) of rain is forecast for Sydney, and as much as 300mm for the lower Blue Mountains, west of the city.
Agata Imielska from the Bureau of Meteorology warned of localised intense rainfall and damaging winds, saying the public should be aware of "dangerous conditions" that can change quite quickly.
"If you don't need to travel, if you don't need to head out today, this is the day to stay at home," Ms Imielska was quoted as saying by the Sydney Morning Herald.
More storms are forecast in the coming days, and parts of eastern Australia could receive up to a metre of rain in the space of just a week, the BBC's Phil Mercer in Sydney reports.
source:https://www.bbc.com
Friendly Fire: How Autoantibodies Could Drive Severe COVID-19
source:https://science.thewire.in/
Saturday, 26 December 2020
Study reveals Covid-19 severity is affected by proportion of antibodies targeting crucial viral protein
A recent study has revealed that Covid-19 antibodies wane significantly within several months of infection and preferentially target a different part of the virus in mild cases of Covid-19 than in comparison to severe ones.The findings which were published in Science Immunology identifies new links between the course of the disease and a patient’s immune response to it. They also raise concerns about whether people can be re-infected, whether antibody tests to detect prior infection may underestimate the breadth of the pandemic and whether vaccinations may need to be repeated at regular intervals to maintain a protective immune response.This is one of the most comprehensive studies to date of the antibody immune response to SARS-CoV-2 in people across the entire spectrum of disease severity, from asymptomatic to fatal,” said Scott Boyd, MD, Ph.D., associate professor of pathology. “We assessed multiple time points and sample types, and also analyzed levels of viral RNA in patient nasopharyngeal swabs and blood samples. It’s one of the first big-picture looks at this illness.”The study found that people with severe Covid-19 have low proportions of antibodies targeting the spike protein used by the virus to enter human cells compared with the number of antibodies targeting proteins of the virus’s inner shell.
Boyd is a senior author of the study, which was published December 7 in Science Immunology. Other senior authors are Benjamin Pinsky, MD, Ph.D., associate professor of pathology, and Peter Kim, Ph.D., the Virginia and D. K. Ludwig Professor of Biochemistry. The lead authors are research scientist Katharina Roltgen, Ph.D.; postdoctoral scholars Abigail Powell, Ph.D., and Oliver Wirz, Ph.D.; and clinical instructor Bryan Stevens, MD.
The virus binds to the ACE2 receptor
The researchers studied 254 people with asymptomatic, mild, or severe Covid-19 who were identified either through routine testing or occupational health screening at Stanford Health Care or who came to a Stanford Health Care clinic with symptoms of Covid-19. Of the people with symptoms, 25 were treated as outpatients, 42 were hospitalized outside the intensive care unit and 37 were treated in the intensive care unit. Twenty-five people in the study died of the disease.SARS-CoV-2 binds to human cells via a structure on its surface called the spike protein. This protein binds to a receptor on human cells called ACE2. The binding allows the virus to enter and infect the cell. Once inside, the virus sheds its outer coat to reveal an inner shell encasing its genetic material. Soon, the virus co-opts the cell’s protein-making machinery to churn out more viral particles, which are then released to infect other cells.
Antibodies that recognize and bind to the spike protein block its ability to bind to ACE2, preventing the virus from infecting the cells, whereas antibodies that recognize other viral components are unlikely to prevent viral spread. Current vaccine candidates use portions of the spike protein to stimulate an immune response.Boyd and his colleagues analyzed the levels of three types of antibodies -- IgG, IgM, and IgA -- and the proportions that targeted the viral spike protein or the virus’s inner shell as the disease progressed and patients either recovered or grew sicker. They also measured the levels of viral genetic material in nasopharyngeal samples and blood from the patients. Finally, they assessed the effectiveness of the antibodies in preventing the spike protein from binding to ACE2 in a laboratory dish.
“Although previous studies have assessed the overall antibody response to infection, we compared the viral proteins targeted by these antibodies,” Boyd said. “We found that the severity of the illness correlates with the ratio of antibodies recognizing domains of the spike protein compared with other nonprotective viral targets. Those people with mild illness tended to have a higher proportion of anti-spike antibodies, and those who died from their disease had more antibodies that recognized other parts of the virus.”
Substantial variability in the immune response
The researchers caution, however, that although the study identified trends among a group of patients, there is still substantial variability in the immune response mounted by individual patients, particularly those with severe disease.
“Antibody responses are not likely to be the sole determinant of someone’s outcome,” Boyd said. “Among people with severe disease, some die, and some recover. Some of these patients mount a vigorous immune response, and others have a more moderate response. So, there are a lot of other things going on. There are also other branches of the immune system involved. It’s important to note that our results identify correlations but don’t prove causation.”
As in other studies, the researchers found that people with asymptomatic and mild illness had lower levels of antibodies overall than did those with severe disease. After recovery, the levels of IgM and IgA decreased steadily to low or undetectable levels in most patients over a period of about one to four months after symptom onset or estimated infection date, and IgG levels dropped significantly.“This is quite consistent with what has been seen with other coronaviruses that regularly circulate in our communities to cause the common cold,” Boyd said. “It’s not uncommon for someone to get re-infected within a year or sometimes sooner. It remains to be seen whether the immune response to SARS-CoV-2 vaccination is stronger, or persists longer than that caused by natural infection. It’s quite possible it could be better. But there are a lot of questions that still need to be answered.”
Boyd is a co-chair of the National Cancer Institute’s SeroNet Serological Sciences Network, one of the nation’s largest coordinated research efforts to study the immune response to Covid-19. He is the principal investigator of the Centre of Excellence in SeroNet at Stanford, which is tackling critical questions about the mechanisms and duration of immunity to SARS-CoV-2.“For example, if someone has already been infected, should they get the vaccine? If so, how should they be prioritized?” Boyd said. “How can we adapt seroprevalence studies in vaccinated populations? How will immunity from vaccination differ from that caused by a natural infection? And how long might a vaccine be protective? These are all very interesting, important questions.”
source:https://www.hindustantimes.com
Wednesday, 16 December 2020
Saturday, 7 November 2020
Earth Observation Satellite Is ISRO's First Launch Since Covid Lockdown
ISRO Satellite Launch: EOS-01 is an earth observation satellite intended for applications in agriculture, forestry and disaster management support
Bengaluru: ISRO (Indian Space Research Organisation) has successfully launched its latest earth observation satellite (EOS-01), as well as nine satellites from customer nations, onboard the PSLV-C49 launch vehicle from the Satish Dhawan Space Centre in Andhra Pradesh's Sriharikota on Saturday evening.
This is the space agency's first launch since a nationwide coronavirus lockdown was initiated by Prime Minister Narendra Modi on March 23. An earlier launch - of the GSAT-30 telecommunication satellite - was completed in January, but that was from a base in French Guinea.
The launch took place at 3.12 PM after a 26-hour countdown. The launch was delayed by 10 minutes due to bad weather and debris in the flight path, ISRO sources told news agency PTI.
At 3.34 pm ISRO said the customer satellites had separated and been injected into their intended orbits. Six minutes earlier the space agency said India's EOS-01 satellite had separated from the fourth stage of the PSLV (Polar Satellite Launch Vehicle) rocket and been injected into orbit.
The PSLV is often referred to as the workhorse of India's space programme and has now completed its 51st launch. Today was also the 77th launch mission from the Sriharikota spaceport. Today's launch also means the agency has sent 328 foreign satellites (from 33 nations) into space.
According to ISRO, EOS-01 is a highly advanced earth observation satellite intended for use in supporting agriculture, forestry and disaster management planning.
The customer satellites, launched under a commercial agreement with NewIndia Space Limited (NSIL), include four from the United States that are meant for "multi-mission remote sensing".
Four of the remaining five are from Luxembourg (for maritime applications) and the other is from Lithuania (for technology demonstration).
Source:-https://www.ndtv.com/
Thursday, 13 August 2020
2 Cops Killed As Terrorists Fire At Police Team On Outskirts Of Srinagar
Srinagar: Two Jammu and Kashmir policemen were killed and another was injured after a police party came under attack from terrorists on the outskirts of Srinagar this morning, the police said.
The police party was on routine security duty at Nowgam Bypass area of the city when it came under heavy firing. After the attack, terrorists managed to escape.
This is the second attack on security forces in last three days. On Wednesday one army soldier was injured after a Quick Reaction Team (QRT) of the army was attacked at Hygam along Srinagar- Baramulla highway.
Today's attack has come ahead of Independence Day when security is on all-time high alert in Kashmir.
In a statement the police said three police personnel were injured in the attack and were shifted to hospital for treatment. Two of them died during treatment, police said.
"Terrorists fired indiscriminately upon police party near Nowgam Bypass. 3 police personnel injured. They were shifted to hospital for treatment where two among them attained martyrdom. Area cordoned off. Further details shall follow," Kashmir Zone Police tweeted, giving an update on the incident.
Security forces and police have intensified patrolling and troops have been deployed across the city. The main Independence Day function will be held at Sher-e-Kashmir Cricket Stadium in Srinagar.
Officials said that random search of vehicles are being carried out near Sher-e-Kashmir Cricket Stadium, the venue of the main function.
Similar precautionary measures with respect to security arrangements have been made in other districts of the valley, the officials said.
source:https://www.ndtv.com/
Saturday, 20 June 2020
Monday, 8 June 2020
Samosa | घर पर हलवाई जैसे खस्ता समोसे बनाये। Samosa Recipe | Aloo Samosa | instant samosa recipes
INGREDIENTS:
For dough:
All_purpose flour 2cups
Salt 1 tsp
Carom seeds 1/2 tsp
desi ghee /oil 4 tbsp
water 150ml
ingredients for stuffing:
Desi ghee/oil 2 tbsp
Garlic (chopped) 2tbsp
ginger (chopped) 2tbsp
cumin 1 tbsp
green chilies 3 (chopped)
onion one medium size
nigella seeds 1 tsp
salt to taste
red chili powder 1 tsp
red chili flakes 1 tsp
lemon juice 1 tbsp
coriander powder 1 tsp
boiled potatoes 600g
cilantro chopped half a cup
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Hi friends, today I'm sharing halwai style samosa recipe. An Indian samosa is a flaky crust made of all purpose flour and filled with spiced potatoes and peas. Learn how to make perfect samosa recipe.

















